Professor Steven V. Ley Research Group

Publications

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  • Currently displaying 81 - 100 of 1071 publications
Author(s)
Publication title
Journal Name
Publication year
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia
S Picaud, K Leonards, J-P Lambert, O Dovey, C Wells, O Fedorov, O Monteiro, T Fujisawa, C-Y Wang, H Lingard, C Tallant, N Nikbin, L Guetzoyan, R Ingham, SV Ley, P Brennan, S Muller, A Samsonova, A-C Gingras, J Schwaller, G Vassiliou, S Knapp, P Filippakopoulos
Sci Adv
(2016)
2
(doi: 10.1126/sciadv.1600760)
Continuous Processing and Efficient $\textit{in Situ}$ Reaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy
B Ahmed-Omer, E Sliwinski, JP Cerroti, SV Ley
Organic Process Research & Development
(2016)
20
(doi: 10.1021/acs.oprd.6b00177)
The Total Synthesis of the Bioactive Natural Product Plantazolicin A and Its Biosynthetic Precursor Plantazolicin B
S Fenner, ZE Wilson, SV Ley
Chemistry A European Journal
(2016)
22
(doi: 10.1002/chem.201603157)
Flow Chemistry in Europe
V Hessel, SV Ley
Journal of Flow Chemistry
(2016)
6
(doi: 10.1556/1846.2016.22222)
Taming hazardous chemistry by continuous flow technology
M Movsisyan, EIP Delbeke, JKET Berton, C Battilocchio, SV Ley, CV Stevens
Chemical Society reviews
(2016)
45
(doi: 10.1039/c5cs00902b)
A multicomponent approach for the preparation of homoallylic alcohols.
J-S Poh, S-H Lau, IG Dykes, DN Tran, C Battilocchio, SV Ley
Chem Sci
(2016)
7
(doi: 10.1039/c6sc02581a)
Synthesis of trifluoromethylated isoxazoles and their elaboration through inter- and intra-molecular C-H arylation
J-S Poh, C García-Ruiz, A Zúñiga, F Meroni, DC Blakemore, DL Browne, SV Ley
Organic and Biomolecular Chemistry
(2016)
14
(doi: 10.1039/c6ob00970k)
Identification and Development of 2,3-Dihydropyrrolo[1,2‑a]quinazolin-5(1H)‑one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex
CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, P Siejka, S Müller, S Knapp, JD Brenton, PE Brennan, SV Ley
J Med Chem
(2016)
59
(doi: 10.1021/acs.jmedchem.5b01997)
Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification
T Ouchi, RJ Mutton, V Rojas, DE Fitzpatrick, DG Cork, C Battilocchio, SV Ley
ACS Sustainable Chemistry and Engineering
(2016)
4
(doi: 10.1021/acssuschemeng.6b00287)
Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification
T Ouchi, RJ Mutton, V Rojas, DE Fitzpatrick, DG Cork, C Battilocchio, SV Ley
ACS Sustainable Chemistry & Engineering
(2016)
4
(doi: 10.1021/acssuschemeng.6b00287)
Development of the industrial synthesis of vitamin A
GL Parker, LK Smith, IR Baxendale
Tetrahedron
(2016)
72
(doi: 10.1016/j.tet.2016.02.029)
The Generation of a Library of ­Bromodomain‐Containing Protein Modulators Expedited by Continuous Flow Synthesis
P Filipponi, IR Baxendale
European Journal of Organic Chemistry
(2016)
2016
(doi: 10.1002/ejoc.201600222)
Enabling Technologies for the Future of Chemical Synthesis.
DE Fitzpatrick, C Battilocchio, SV Ley
ACS central science
(2016)
2
(doi: 10.1021/acscentsci.6b00015)
Iterative reactions of transient boronic acids enable sequential C-C bond formation.
C Battilocchio, F Feist, A Hafner, M Simon, DN Tran, DM Allwood, DC Blakemore, SV Ley
Nat Chem
(2016)
8
(doi: 10.1038/nchem.2439)
Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry.
D Lücke, T Dalton, SV Ley, ZE Wilson
Chemistry (Weinheim an der Bergstrasse, Germany)
(2016)
22
(doi: 10.1002/chem.201504457)
A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process.
J-S Poh, DL Browne, SV Ley
Reaction Chemistry and Engineering
(2016)
1
(doi: 10.1039/c5re00082c)
Welcome to Reaction Chemistry & Engineering
SA Khan, IR Baxendale, JM Hawkins, SV Ley, K Jensen, V Hessel, G Luo, D Blackmond, A Katz, DG Vlachos, ME Davis
Reaction Chemistry & Engineering
(2016)
1
(doi: 10.1039/c6re90001a)
Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors
N Holmes, GR Akien, RJD Savage, C Stanetty, IR Baxendale, AJ Blacker, BA Taylor, RL Woodward, RE Meadows, RA Bourne
Reaction Chemistry & Engineering
(2016)
1
(doi: 10.1039/c5re00083a)
Controlled generation and use of CO in flow (vol 1, pg 280, 2016)
SVF Hansen, ZE Wilson, T Ulven, SV Ley
Reaction Chemistry & Engineering
(2016)
1
(doi: 10.1039/c6re90010k)
Flow enabled peptide synthesis
Z Wilson, S Ley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252

Papers of Interest

Yusuf Hamied Department of Chemistry
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