Synthesis constitutes the design and assembly of the majority of Society's functional molecules. As such the technologies and methods of synthesis are evolving constantly in response to our planetary resources and the drive to more sustainable processes. All our research has been dedicated towards improving synthesis procedures with the invention of new reagents and processes in new bond forming events.
There is considerable overlap of projects across our research portfolio and virtually all publications express some key element of synthesis. The work covers a diverse array of research topics in over 900 published papers, book chapters and reviews.
Specific areas of interest:
Synthesis Methods Reviews:
- Continuous flow synthesis enabling reaction discovery (2024)
- The Evolution of Flow Chemistry: An Opinion on Factors Driving Innovation (2023)
- Process Intensification: From Green Chemistry to Continuous Processing in Sustainable Organic Synthesis: Tools and Strategies (2021 - Print ISBN978-1-83916-203-9; ePub eISBN978-1-83916-485-9).
- Formation and Utility of Reactive Ketene Intermediates Under Continuous Flow Conditions (2021)
- Living with our machines: Towards a more sustainable future (2020)
- A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions (2020)
- Engineering chemistry for the future of organic synthesis (2018)
- Taming hazardous chemistry by continuous flow technology (2016)
- The ‘Internet of Chemical Things‘ (2015)
- Machine-assisted organic synthesis (2015)
- Organic synthesis: march of the machines (2015)
- Flow chemistry meets advanced functional materials (2014)
- Continuous flow chemistry: a discovery tool for new chemical reactivity patterns (2014)
- Camera enabled techniques for organic synthesis (2013)
- On being green: can flow chemistry help? (2012)
- Less well Known enabling technologies for organic synthesis (2011)
- Lab of the future: the importance of remote monitoring and control (2011)
- The changing face of organic synthesis (2010)
- Practical Organocatalysis with (S)- and (R)-5 Pyrrolidin-2-yl-1H-tetrazoles (2008)
- A Fascination with 1,2-Diacetals (2007)
- Asymmetric Organocatalysis (2006 - ISBN-978-3-527-31399-0, 211-216)
- Synthesis of the Thapsigargins (2004)
- Organic Synthesis in a Changing World (2002)
- New Tools and Concepts in Modern Organic Synthesis (2002)
- The Development and Application of Supported Reagents for Multi-step Organic Synthesis (2001)
- 1,2- Diacetals: A New Opportunity for Organic Synthesis (2001)
- Multistep Organic Synthesis using Solid Supported Reagents and Scavengers: A New Paradigm in Chemical Library Generation (2000)
- π-Allyltricarbonyliron lactone complexes in organic synthesis: a useful and conceptually unusual route to lactones and lactams (1996)
- Tetrapropylammonium perruthanate, Pr4N+RuO4- TPAP: a catalytic oxidant for organic synthesis (1994)
- Tricarbonyliron lactone complexes in organic synthesis (1994)
- The Champagne Route to Avermectins and Milbemycins (1991)
