Professor Steven V. Ley Research Group

Publications

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  • Currently displaying 421 - 440 of 1027 publications
Author(s)
Publication title
Journal Name
Publication year
Targeting C-reactive protein for the treatment of cardiovascular disease.
MB Pepys, GM Hirschfield, GA Tennent, JR Gallimore, MC Kahan, V Bellotti, PN Hawkins, RM Myers, MD Smith, A Polara, AJA Cobb, SV Ley, JA Aquilina, CV Robinson, I Sharif, GA Gray, CA Sabin, MC Jenvey, SE Kolstoe, D Thompson, SP Wood
Nature
(2006)
440
(doi: 10.1038/nature04672)
Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives.
G Zinzalla, L-G Milroy, SV Ley
Organic & biomolecular chemistry
(2006)
4
(doi: 10.1039/b603015g)
An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones
CET Mitchell, SE Brenner, J García-Fortanet, SV Ley
Org. Biomol. Chem.
(2006)
4
(doi: 10.1039/b601877g)
A highly enantioselective total synthesis of (+)-goniodiol.
EW Tate, DJ Dixon, SV Ley
Org Biomol Chem
(2006)
4
(doi: 10.1039/b602805e)
A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: A new paradigm for molecular assembly
IR Baxendale, J Deeley, CM Griffiths-Jones, SV Ley, S Saaby, GK Tranmer
Chem Commun (Camb)
(2006)
(doi: 10.1039/b600382f)
Practical Synthesis of ( S )-Pyrrolidin-2-yl-1 H -tetrazole, Incorporating Efficient Protecting Group Removal by Flow-Reactor Hydrogenolysis
S Ley, V Franckevičius, K Knudsen, M Ladlow, D Longbottom
Synlett
(2006)
2006
(doi: 10.1055/s-2006-939036)
Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives
KR Knudsen, AF Stepan, P Michel, SV Ley
Organic & biomolecular chemistry
(2006)
4
(doi: 10.1039/b601888b)
Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems To Generate Protected 1,3-Dicarbonyl Compounds
HF Sneddon, A van den Heuvel, AKH Hirsch, RA Booth, DM Shaw, MJ Gaunt, SV Ley
The Journal of Organic Chemistry
(2006)
71
(doi: 10.1021/jo052514s)
Preparation of the neolignan natural product grossamide by a continuous-flow process
S Ley, I Baxendale, C Griffiths-Jones, G Tranmer
Synlett
(2006)
2006
(doi: 10.1055/S-2006-926244)
A new strategy for oligosaccharide assembly exploiting cyclohexane-1,2-diacetal methodology: An efficient synthesis of a high mannose type nonasaccharide
P Grice, SV Ley, J Pietruszka, HMI Osborn, HWM Priepke, SL Warriner
Chemistry - A European Journal
(2006)
3
(doi: 10.1002/chem.19970030315)
Sexual development of malaria parasites is inhibited in vitro by the neem extract azadirachtin, and its semi-synthetic analogues.
IW Jones, AA Denholm, SV Ley, H Lovell, A Wood, RE Sinden
FEMS microbiology letters
(2006)
120
(doi: 10.1111/j.1574-6968.1994.tb07044.x)
Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives (vol 4, pg 1471, 2006)
KR Knudsen, AF Stepan, P Michel, SV Ley
ORG BIOMOL CHEM
(2006)
4
Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst
KR Knudsen, CET Mitchell, SV Ley
Chem Commun (Camb)
(2005)
(doi: 10.1039/b514636d)
Defects in signal transduction caused by a T cell receptor beta chain substitution.
TA Reno, S Ley, E Sugiyama, A Cantagrel, R Blumberg, J Bonventre, C Terhorst, ET Yeh
Eur J Immunol
(2005)
20
(doi: 10.1002/eji.1830200702)
Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives.
SV Ley, DJ Dixon, RT Guy, F Rodríguez, TD Sheppard
Org Biomol Chem
(2005)
3
(doi: 10.1039/b512410g)
Evolution or Revolution: The Challenge to the Modern Medicinal Chemist
IR Baxendale, SV Ley
(2005)
Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin
H Søhoel, T Liljefors, SV Ley, SF Oliver, A Antonello, MD Smith, CE Olsen, JT Isaacs, SB Christensen
J Med Chem
(2005)
48
(doi: 10.1021/jm058036v)
Synthesis of Alkaloid Natural Products Using Solid-Supported Reagents and Scavengers
I Baxendale, S Ley
Current Organic Chemistry
(2005)
9
(doi: 10.2174/138527205774370513)
A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones.
CET Mitchell, SE Brenner, SV Ley
Chemical Communications
(2005)
(doi: 10.1039/b511441a)
Quaternary Stereocenters
P Nolan
(2005)
(doi: 10.1002/3527606858)

Papers of Interest

Yusuf Hamied Department of Chemistry
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enquiries@ch.cam.ac.uk
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