| 1980 | Corday Morgan Medal and Prize (Royal Society of Chemistry, RSC) |
| 1981 | The 1981-1983 Hickinbottom Research Fellowship (joint 1st recipient) (RSC) |
| 1983 | Pfizer Academic Award (1st recipient) (Pfizer PLC) |
| 1988 | Tilden Lectureship and Medal (Royal Society of Chemistry) |
| 1989 | Award for Organic Synthesis (Royal Society of Chemistry) |
| 1992 | Pedler Lectureship, Medal and Prize (Royal Society of Chemistry) |
| 1993 | Simonsen Lectureship and Medal (Royal Society of Chemistry) |
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1993 |
Award for Natural Product Chemistry (Royal Society of Chemistry) |
| 1994 | Adolf Windaus Medal (German Chemical Society - Georg-August University, Göttingen) |
| 1995 | The Novartis Research Fellowship (1995 - 2007) (Novartis) |
| 1995 | The Flintoff Medal (Royal Society of Chemistry) |
| 1995 | The Dr. Paul Janssen Prize for Creativity in Organic Synthesis (Janssen Research Foundation) |
| 1996 | George Kenner Award and Lectureship (University of Liverpool) |
| 1997 | The Bakerian Lecturer (The Royal Society) |
| 1998 | The Rhône-Poulenc Lectureship, Medal and Prize (Royal Society of Chemistry) |
| 1999 | The GlaxoWellcome Award for Outstanding Achievement in Organic Chemistry (1st recipient) |
| 2000 | The Davy Medal (The Royal Society) |
| 2001 | Haworth Memorial Lectureship, Medal and Prize (Royal Society of Chemistry) |
| 2001 | August-Wilhelm-von Hofmann Medal (Gesellschaft Deutscher Chemiker) |
| 2001 | The Pfizer Award for Innovative Science (1st chemist recipient) (Pfizer Global R & D) |
| 2003 | The Ernest Guenther Award in the Chemistry of Natural Products (American Chemical Society) |
| 2003 | Royal Society Wolfson Merit Award |
| 2003 | Award in Carbohydrate Chemistry (Royal Society of Chemistry) |
| 2004 | The Messel Medal (The Society of Chemical Industry) |
| 2004 | Innovation of the Year Award: Jointly with AstraZeneca, Avecia and Syngenta (Chemical Industries Association) |
| 2004 | iChemE Award for Innovation in Applied Catalysis. (The iAc Award) |
| 2004 | Teamwork in Innovation Award (Royal Society of Chemistry) |
| 2004 | Alexander-von-Humboldt Award (Germany) |
| 2005 | The Yamada-Koga Prize (Japan Research Foundation for Optically Active Compounds) |
| 2006 | The Robert Robinson Lectureship, Medal and Prize (Royal Society of Chemistry) |
| 2006 | The Nagoya Gold Medal (Banyu Life Science Foundation International, Japan) |
| 2006 | Thomson Scientific Laureate in Chemistry |
| 2007 | Award for Creative Work in Synthetic Organic Chemistry (American Chemical Society) |
| 2007 | Paul Karrer Gold Medal (University of Zürich, Switzerland) |
| 2007 | The SCI Innovation Award (Society of Chemical Industry-1st recipient) |
| 2007 | Société Française de Chimie, Medal on the Occasion of 150th Anniversary |
| 2008 | Hans Herloff Inhoffen Medal, Helmholtz Zentrum für Infektionsforschung, Germany |
| 2008 | Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery (European Federation of Medicinal Chemistry) |
| 2008 | High Throughput Drug Discovery Methodologies Award (Royal Society of Chemistry) |
| 2009 | U.R. Ghatak Endowment Lecture and Gold Medal (Indian Association for the Cultivation of Science, India) |
| 2009 | Perkin Prize for Organic Chemistry, (Royal Society of Chemistry – 1st recipient) |
| 2009 | The Tetrahedron Prize for Creativity in Organic Chemistry (Elsevier) |
| 2009 | Heinrich Wieland Prize (Boehringer Ingelheim, Germany) |
| 2010 | The Paracelsus Prize (Swiss Chemical Society) |
| 2011 | The Royal Medal (Royal Society) |
| 2013 | The Longstaff Prize (Royal Society of Chemistry) |
| 2013 | Société Chimique de France SCF, Franco-Britannique Prize |
| 2014 | IUPAC-Thales Nano Prize in Flow Chemistry |
| 2018 | Arthur C. Cope Award (American Chemical Society) |